The 13.1-mile, rolling course features a combined loop and out-and-back route, beginning and ending at Roberto Clemente Field in the Back Bay Fens neighborhood of Boston (also known as the Fenway). With a start on Park Drive adjacent to Roberto Clemente Field, the course proceeds through the Riverway and over Route 9 into Brookline. The course then passes Jamaica Pond and the Arborway on its way to Franklin Park, with a turnaround in the Franklin Park Zoo.

Returning from Franklin Park, the course follows the Arborway to the Jamaicaway to the Riverway before finishing back in the Fenway neighborhood at Roberto Clemente Field.

Start - Mile 1:
Back Bay Fens and Riverway
The race begins on the north side of Roberto Clemente Field on Park Dr. at Kilmarnock St. in the Back Bay Fens, heading north. The course takes a left on the Riverway -- around the rotary -- in front of the Landmark Center, and proceeds along the Riverway past Longwood Ave.

Mile 2 - 3:
Riverway, Olmsted Park, and Jamica Pond
Remaining on the Riverway, the course takes a right exit immediately after crossing over Route 9 (Boylston St.), near the Brookline/Boston town line. There, it picks up the beginning of Pond Ave. in Brookline in front of the Brook House. The course continues on Pond Ave., passing Olmsted Park on its way around the rotary at Pond and Chestnut St. Through the rotary, the course takes Chestnut St., continuing south and running towards Jamaica Pond. After a right onto Perkins St., the course keeps Jamaica Pond on its left and takes a left onto Parkman Dr. (Jamaica Park is on the right side of the course).

Mile 4:
Arborway and Arnold Arboretum
At the end of Parkman Dr., the course takes a right onto Pond St. where the Jamaicaway meets the Arborway, continuing on the Arborway and the rotary at Center St. Still on the Arborway, the course passes Arnold Arboretum on the right and continues on the overpass above Forest Hills.

Mile 5 - 7:
Forest Hills Overpass, Franklin Park, and Zoo
At the base of the overpass, the course enters Franklin Park on Circuit Dr. via the rotary in front of Morton St. and Forest Hills Cemetary. In the park, the course continues on Circuit Dr. and enters the Franklin Park Zoo at the entrance near The Playstead and White Stadium (South Entrance). After a short loop within the zoo, the route exits the zoo from the same entrance, and exits Franklin Park via the same route as it entered (Circuit Dr.).

Mile 8 - 10:
Arborway, Jamaicaway, Riverway
Heading back towards the start/finish venue, the course follows the Arborway to the Jamaicaway to the Riverway. Note: the course passes to the south of Jamaica Pond on the return, as well as staying on the south of Olmsted Park (within Boston's city limits).

Mile 11:
Riverway
Continuing over Route 9, the course travels along the Riverway to the Fenway (just prior to the Park Drive/Brookline Ave. Rotary in front of the Landmark Center.

Mile 12 - 13.1:
Fenway and Finish at Roberto Clemente Field
The final mile brings runners into the Fenway via a right hand turn at Park Dr. Running the perimeter of the Fenway, the course passes the Museum of Fine Arts on the right and makes its run to the finish in a counter clockwise direction around the Fens, meeting Roberto Clemente Field from Park Dr. (north).